Vampire teeth: Also known as the vampire disorder, people who suffer from Hypohidrotic ectodermal dysplasia often have pointed teeth, making them look eerily similar to the blood-sucking creatures of fiction. This disorder can also affect hair, skin, and nails. Severe cases of HED are characterized by thin, pale bodies with dark circles under and around the eyes, pointed or missing teeth, no hair, and signs of premature aging. Most people who suffer from HED must constantly manage and check their body temperature, while remaining out of the sunlight and heat for long periods of time due to their lack of sweat glands. This is the most common form of ectodermal dysplasia, affecting one in every 17,000 people, including actor Michael Berryman.(Fig. 185)
Hypohidrotic ectodermal dysplasia is one of about 150 types of ectodermal dysplasia in humans. Before birth, these disorders result in the abnormal development of structures including the skin, hair, nails, teeth, and sweat glands. Most people with hypohidrotic ectodermal dysplasia have a reduced ability to sweat (hypohidrosis) because they have fewer sweat glands than normal or their sweat glands do not function properly. Sweating is a major way that the body controls its temperature; as sweat evaporates from the skin, it cools the body. An inability to sweat can lead to a dangerously high body temperature (hyperthermia), particularly in hot weather. In some cases, hyperthermia can cause life-threatening medical problems.
Affected individuals tend to have sparse scalp and body hair (hypotrichosis). The hair is often light-colored, brittle, and slow-growing. This condition is also characterized by absent teeth (hypodontia) or teeth that are malformed. The teeth that are present are frequently small and pointed.
Hypohidrotic ectodermal dysplasia is associated with distinctive facial features including a prominent forehead, thick lips, and a flattened bridge of the nose. Additional features of this condition include thin, wrinkled, and dark-colored skin around the eyes; chronic skin problems such as eczema; and a bad-smelling discharge from the nose (ozena).
Hypohidrotic ectodermal dysplasia has several different inheritance patterns. Most cases are caused by mutations in the EDA gene, which are inherited in an X-linked recessive pattern. A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation must be present in both copies of the gene to cause the disorder. Males are affected by X-linked recessive disorders much more frequently than females. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons.
In X-linked recessive inheritance, a female with one altered copy of the gene in each cell is called a carrier. In about 70 percent of cases, carriers of hypohidrotic ectodermal dysplasia experience some features of the condition. These signs and symptoms are usually mild and include a few missing or abnormal teeth, sparse hair, and some problems with sweat gland function. Some carriers, however, have more severe features of this disorder.
Kicked Out of Heaven Vol. II
Now Available $54.00
The Untold History of The White Races cir. 700 – 1700 a.d.
666 pages 197 pages
- ISBN-10: 1943820058
- ISBN-13: 978-1943820054
ONLY 2 COPIES LEFT!
Kicked Out Of Heaven Vol. II: The Untold History of The White Races cir. 700-1700 a.d. is a 3 volume series that will be released one by one. This book details everything about European society and mentality. In this edition you will find these facts: Alcoholism & The Blue Devils, Insanity & Lead Poisoning, Ergot (LSD) Hallucinations, The Sweating Sickness & Leprosy, The Tobacco Enema & Leeches, The Defloration Mania, The Dancing Mania, The Black Death, The Gravediggers & Body Snatchers, Jews Poisoning the Wells, Millions of Deaths, Folklore & Superstition, Magic Mirrors & Crystal Balls, Witches Dancing in Baby Blood, Pants Made of Human Skin, Necromancy & Ghost Armies, Attacks from The Undead, Lycanthropy & Were-Wolves, Multiple Cases of Vampires, Who is Satan, Lucifer & The Devil!
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